WPShapere plugin can support WordPress Multi-site installation too. In a Multi-site network installation, you can let your network blog admins have their own Admin Panel customizations, or You (as Network Super Admin) take control over all network blogs admin panel customizations (Global Customization).
By default, Global customization has been enabled in the plugin. If you want to allow other blog admins under your network to customize the admin area by themselves, delete or comment the following codes in /wpshapere/wpshapere.php
if(is_multisite())
define('NETWORK_ADMIN_CONTROL', true);